Cambiasso Laboratory

Dr. María Julia Cambiasso

Dr. María Julia Cambiasso graduated in Biology from the Universidad Nacional de Córdoba (UNC), Argentina and obtained her Ph.D. in Biology from the same university in 1999. Afterwards, she moved to Europe to conduct her post-doctoral studies in the Department of Anatomy and Cell Biology at Ulm University under the supervision of Dr. Ingrid Reisert. At present, she is an Independent Researcher of the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a Full Professor of Cell Biology at the School of Dentistry, UNC. She has been directing the Laboratory of Neurophysiology of the Instituto Ferreyra in Córdoba-Argentina since 2010.
Her specialty is the study of molecular and cellular mechanisms involved in the sexual differentiation of the brain with special emphasis on the differential action of the sex chromosome genes and gonadal hormones.

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Associate Researchers

Dr. Carla Cisternas

Dr. Carla Cisternas is an Assistant Investigator of CONICET and an Assistant Professor of Cell Biology at the School of Dentistry of the National University of Córdoba (UNC). In 2015 Dr. Cisternas was the first Dr. in Neuroscience of the UNC. Her dissertation focused on the role of sex chromosomes and gonadal hormones in the sexual differentiation of the brain and was mentored by Dr. Julia Cambiasso. She then carried out postdoctoral stays at the Cajal Institute of Madrid, Spain (2015) mentored by Dr. García Segura and at our institute (2016) mentored by Dr. Julia Cambiasso. In 2016 Dr. Cisternas was appointed a Next Generation Postdoctoral Scholar in Neuroscience at Georgia State University, mentored by Dr. Nancy Forger. Dr. Cisternas returned to Argentina in 2019 and she started her research project in the laboratory of Neurophysiology in 2020. The main focus of her project is to evaluate the role of gonadal steroids in the turnover of methylation and demethylation marks in the DNA during postnatal development of the brain and how these mechanisms could have a role in sex differences in neuropsychiatric disorders.

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Pagliini Laboratory

Dr. Gabriela Paglini

Dra. Paglini earned her Biologist degree at the Universidad Nacional de Córdoba, Faculty of Exact, Physical and Natural Sciences (1987), in Argentina. She graduated from the same institution as a Ph.D. in Biological Sciences (1994).

She was a postdoctoral Fellow in the Laboratory of Molecular and Cellular Neurobiology of the Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, under the menthorship of Dr. Alfredo Cáceres. At the same time, she obtained postdoctoral training in basic experimental virology, under the menthorship of Dr. S. Paglini, in the Virology Institute of the Faculty of Medical Sciences, Universidad Nacional de Córdoba. In the latter institution, she obtained a tenured adjunct professor position that she holds to the present.

Dr. Gabriela Paglini is also a CONICET Independent Researcher and her laboratory is dedicated to two different lines of investigation. The first one is to understand plasticity mechanisms of the brain under the effects of psychostimulants and in cognitive processes. This is guided by the hypothesis that drugs of abuse usurp many of the same cellular and molecular mechanisms involved in the normal mechanisms of reward-related learning and memory.

The second line of research studies the mechanisms underlying Attention-Deficit Hyperactivity Disorder (ADHD), one of the most common neurodevelopmental disorders, with typical onset in childhood and known persistence into adulthood. In this context, animal models of human diseases play a critical role in the exploration and characterization of the pathophysiology and represent a very useful tool in preclinical research to identify, evaluate and validate novel therapeutic agents and treatments. The lab focuses in the behavioral and neurochemical characterization of a transgenic mouse model that recapitulates some key features present in ADHD.

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