Biophysics and Nanotechnology lab
Group leader: Dr. Dolores C. Carrer
PhD student: Ma. Florencia Sanchez
Undergraduate student: Leandro Freites
If you are German or have done your PhD in Germany you can apply to the Alexander von Humboldt Foundation for a postdoctoral fellowship to work with us!
Our lab uses techniques that come from the field of physics to tackle problems relevant to biology and medicine. In particular we use a lot of confocal microscopy and fluorescence correlation spectroscopy, along with cell culture and biochemical methods. We know about lipids and we not only study their behavior in model membranes and cells, but also use them as a tool to build useful technologies, such as functionalized surfaces and nanoparticles for drug delivery.
Study of the effects of the topological manipulation of the ligand in the functioning of synapses
Functionalised surfaces for use in nano and biotechnology have opened a new field in the material sciences. In our case, we build functionalized surfaces with designs controlled at the microscopic level in order to study the effect of the spatial organization of proteins on the response of a stimulated cell.
Nanoparticles for the improved treatment of severe skin diseases
Innovative and highly potent pharmaceutical drugs, such as peptides, proteins and oligonucleotides have frequently a poor stability, are poorly absorbed, rapidly cleaved and difficult to transport to the target site; they can also induce severe adverse reactions. To overcome these problems, nanocarriers are gaining increasing interest. Up til now only a few drugs carried in liposomes have been introduced in the pharmaceutical market worldwide.
We specialise in the design, characterization and study of nanovehicles able to penetrate the skin. We are right now focusing on the treatment of an endemic orphan disease called Leishmaniasis.
We are looking for Master/Diploma/PhD/postdoctoral people to work on this project. Please send your CV to firstname.lastname@example.org
Effects of ceramide on the organization of model biomembranes
We study the behaviour of model membranes that imitate the composition of the plasma membrane of a cell when the apoptotic process is initiated
Alexander von Humboldt